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Spread the tomatoes over 2–3 sheet pans, cut side up, with the garlic and seasonings. Roast at 400°F for 45–75 minutes, rotating pans as needed, until the tomatoes collapse, edges caramelize, and quite a lot of water has evaporated.
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Then scrape everything — juices included — into a large pot.
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From there, you have two directions:
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- Rustic sauce: mash with a potato masher and simmer another 20–40 minutes.
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- Smooth sauce: use an immersion blender, then simmer to your desired thickness.
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If skins bother you, you can run it through a food mill after roasting. Personally, for a big homemade batch, I’d leave them unless they’re especially tough.
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Ten pounds of fresh tomatoes will usually give you roughly 5–7 quarts of sauce before aggressive reduction, depending heavily on how watery the tomatoes are. If you reduce it to a thicker pasta-sauce consistency, expect less.